How FEED Boosts the Immune System

How FEED Boosts the Immune System

FEED {gut+immune} has been formulated to boost the immune system through mechanisms in the gut, with each ingredient specifically chosen to boost immunity and improve gut health.

Prebiotics and Their Function in Immunity 

Partially hydrolysed guar gum (PHGG) and Acacia gum (AG) can contribute to improving the immune system through several mechanisms.

Promotes Gut Health
  • Prebiotic Effect: PHGG+ AG serve as a food source for beneficial gut bacteria (probiotics), such as Bifidobacteria and Lactobacilli. By promoting the growth and activity of these beneficial microbes, these ingredients help maintain a healthy gut microbiota balance, which is crucial for a well-functioning immune system.
  • Short-Chain Fatty Acids (SCFAs) Production: As gut bacteria ferment the prebiotics they produce SCFAs like butyrate, acetate, and propionate. SCFAs have anti-inflammatory properties and play a role in maintaining the integrity of the gut lining, preventing the entry of pathogens and toxins into the bloodstream. 
Enhances Immune Responses
  • Modulates Immune Cell Activity: SCFAs derived from PHGG +AG fermentation can influence the activity of various immune cells, including macrophages, dendritic cells, and T cells. This modulation helps in balancing immune responses, reducing inflammation, and enhancing the body's ability to fight infections.
  • Increases Immunoglobulin Production: PHGG can stimulate the production of immunoglobulins, such as IgA, in the gut. IgA is crucial for immune function as it helps neutralise pathogens and prevent their attachment to the mucosal surfaces.
Enhances Barrier Function
  • Gut Barrier Integrity: By promoting a healthy gut microbiota and the production of SCFAs, PHGG helps strengthen the gut barrier. A strong gut barrier prevents the translocation of harmful bacteria and their toxins into the bloodstream, thereby reducing systemic inflammation and supporting overall immune health.
Prevents Pathogen Colonisation
  • Competitive Exclusion: By fostering a diverse and robust population of beneficial bacteria, PHGG helps outcompete pathogenic bacteria for resources and space in the gut, thereby preventing their colonization and reducing the risk of infections.

    The prebiotics used in FEED enhance immune function primarily by improving gut health, fostering a beneficial microbiota, producing anti-inflammatory SCFAs, strengthening the gut barrier, and preventing pathogen colonisation. This multifaceted approach helps in maintaining a balanced and effective immune response.

    Probiotics and the Immune System

    Similar to prebiotics, the probiotics found in FEED promote a healthy balance of gut bacteria, support the integrity of the gut lining, and produce bioactive metabolites (SCFA) with antimicrobial properties. This creates an environment that is less hospitable to pathogenic bacteria, reduces systemic inflammation, and improves overall gut health, which is crucial for a robust immune system. 

    These specific probiotics also stimulate the immune system directly by enhancing the production of various immune cells and secretory IgA.

    Vitamin D3 and the Immune System

    Vitamin D3 boosts immunity by enhancing the function of both innate and adaptive immune systems. It increases the production of antimicrobial peptides, enhances phagocytosis, modulates T and B cell activity, regulates cytokine production, supports epithelial barrier function, and promotes mucosal immunity.

    These combined effects help protect against infections, control inflammation, and maintain a balanced immune response.

    Why add K2 to FEED?

    Enhanced Calcium Utilization
    • Vitamin D3’s Role: Vitamin D3 enhances the absorption of calcium from the gut into the bloodstream. This is crucial for maintaining adequate calcium levels for various bodily functions, including bone health.
    • Vitamin K2’s Role: Vitamin K2 activates proteins like osteocalcin and matrix Gla-protein (MGP), which help direct calcium to the bones and teeth and away from soft tissues such as arteries and kidneys. This ensures that calcium is used effectively and reduces the risk of calcification in the wrong areas.

    FEED {gut+immune} helps:

    — Relieve constipation

    — Reduce bloating

    —Boost your immune system

    — Support hair, skin and nail growth

    — Improve IBS symptoms




    McFarland L. V. (2010). Systematic review and meta-analysis of Saccharomyces boulardii in adult patients. World journal of gastroenterology, 16(18), 2202–2222.

    Mu, Y., & Cong, Y. (2019). Bacillus coagulans and its applications in medicine. Beneficial microbes, 10(6), 679–688

    Gupta, A. K., & Maity, C. (2021). Efficacy and safety of Bacillus coagulans LBSC in irritable bowel syndrome: A prospective, interventional, randomized, double-blind, placebo-controlled clinical study [CONSORT Compliant]. Medicine, 100(3), e23641.

    Jäger, R., Purpura, M., Farmer, S., Cash, H. A., & Keller, D. (2018). Probiotic Bacillus coagulans GBI-30, 6086 Improves Protein Absorption and Utilization. Probiotics and antimicrobial proteins, 10(4), 611–615.

    McFarland L. V. (2010). Systematic review and meta-analysis of Saccharomyces boulardii in adult patients. World journal of gastroenterology, 16(18), 2202–2222.

    Rawi, M. H., Abdullah, A., Ismail, A., & Sarbini, S. R. (2021). Manipulation of Gut Microbiota Using Acacia Gum Polysaccharide. ACS omega, 6(28), 17782–17797.

    Massot-Cladera, M., Azagra-Boronat, I., Franch, À., Castell, M., Rodríguez-Lagunas, M. J., & Pérez-Cano, F. J. (2020). Gut Health-Promoting Benefits of a Dietary Supplement of Vitamins with Inulin and Acacia Fibers in Rats. Nutrients, 12(8), 2196.

    National Health and Medical Research Council, Australian Government Department of Health and Ageing, New Zealand Ministry of Health. Nutrient Reference Values forAustralia and New Zealand. Canberra: National Health and Medical Research Council; Version 1.2, September 2017.

    Niv E, Halak A, Tiommny E, Yanai H, Strul H, Naftali T, Vaisman N. Randomised clinical study: partially hydrolysed guar gum (PHGG) versus placebo in the treatment of patientswith irritable bowel syndrome. Nutr Metab 2016; 13 (10).

    Aranow C. Vitamin D and the immune system. J Investig Med. 2011 Aug;59(6):881-6. doi: 10.2310/JIM.0b013e31821b8755. PMID: 21527855; PMCID: PMC3166406.

    Martens PJ, Gysemans C, Verstuyf A, Mathieu AC. Vitamin D's Effect on Immune Function. Nutrients. 2020 Apr 28;12(5):1248. doi: 10.3390/nu12051248. PMID: 32353972; PMCID: PMC7281985.

    Ao T, Kikuta J, Ishii M. The Effects of Vitamin D on Immune System and Inflammatory Diseases. Biomolecules. 2021 Nov 3;11(11):1624. doi: 10.3390/biom11111624. PMID: 34827621; PMCID: PMC8615708.

    van Ballegooijen AJ, Pilz S, Tomaschitz A, Grübler MR, Verheyen N. The Synergistic Interplay between Vitamins D and K for Bone and Cardiovascular Health: A Narrative Review. Int J Endocrinol. 2017;2017:7454376. doi: 10.1155/2017/7454376. Epub 2017 Sep 12. PMID: 29138634; PMCID: PMC5613455.

    van Ballegooijen AJ, Beulens JW. The Role of Vitamin K Status in Cardiovascular Health: Evidence from Observational and Clinical Studies. Curr Nutr Rep. 2017;6(3):197-205. doi: 10.1007/s13668-017-0208-8. Epub 2017 Jul 10. PMID: 28944098; PMCID: PMC5585988.

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