The Gut-Brain Axis Unveiled: How Your Gut Health Impacts Mental Wellness

The Gut-Brain Axis Unveiled: How Your Gut Health Impacts Mental Wellness

The human body is a marvel of interconnected systems, and one of the most fascinating relationships exists between the gut and the brain. Long considered as independent entities, emerging research has uncovered a complex network of communication known as the gut-brain axis. This bidirectional interaction plays a crucial role in maintaining overall health and well-being.

I. Anatomy of the Gut-Brain Axis:

A. The Enteric Nervous System (ENS): 1. Often referred to as the "second brain," the ENS is a complex network of neurons embedded in the walls of the gastrointestinal tract. 2. Controls various digestive processes independently but communicates with the central nervous system (CNS) through the vagus nerve.

B. Vagus Nerve: 1. A major player in the gut-brain axis, the vagus nerve is a long cranial nerve that extends from the brainstem to the abdomen. 2. Transmits signals bidirectionally, allowing communication between the gut and the brain.

II. Signalling Molecules and Neurotransmitters:

A. Serotonin: 1. Predominantly produced in the gut, serotonin influences mood, appetite, and sleep. 2. Regulates intestinal movements and helps coordinate communication with the brain.

B. Gut Microbiota: 1. Trillions of microorganisms inhabit the gastrointestinal tract, collectively known as the gut microbiota. 2. Produce neurotransmitters and short-chain fatty acids that influence brain function and behaviour.

III. Impact on Mental Health:

A. Anxiety and Depression: 1. Research suggests a strong link between gut health and mental well-being. 2. Dysbiosis, an imbalance in gut bacteria, has been associated with increased risk of anxiety and depression.

B. Cognitive Function: 1. The gut-brain axis affects cognitive processes, including memory and learning. 2. Inflammation in the gut may contribute to neuro-inflammation and cognitive decline.

IV. Lifestyle Factors:

A. Diet: 1. Certain foods promote a healthy gut microbiota, positively influencing the gut-brain axis. 2. High fibre, fermented foods, and prebiotics support gut health.

B. Stress: 1. Chronic stress can disrupt the gut-brain axis, leading to gastrointestinal issues and mental health problems. 2. Mind-body practices, such as meditation, may positively impact the gut-brain connection.

Conclusion: Understanding the intricate relationship between the gut and the brain opens new avenues for promoting holistic health. As research continues to unveil the mysteries of the gut-brain axis, it becomes increasingly clear that maintaining a healthy gut is not only vital for digestive well-being but also crucial for overall mental and emotional wellness. The choices we make regarding our diet, lifestyle, and stress management can significantly impact this delicate balance, highlighting the importance of a holistic approach to health.

We formulated FEED to ensure the correct supply of pre and probiotics are provided for the gut to enhance its own micribiota which in turn will provide a healthy gut brain axis

REPAIR was formulated to specifically look after the gut lining to repair any holes, reduce gut permeability (leaky gut) and thereby help to reduce inflammation and ensure a healthy gut lining as it houses the enteric nervous system (ENS)

A combination of FEED and REPAIR is the ultimate gut health regime to enhance the gut microbiota and the health of the gut lining helping to improved the gut brain axis and all matters of the brain.

 

References

Appleton J. The Gut-Brain Axis: Influence of Microbiota on Mood and Mental Health. Integr Med (Encinitas). 2018 Aug;17(4):28-32. PMID: 31043907; PMCID: PMC6469458.

Mittal R, Debs LH, Patel AP, Nguyen D, Patel K, O'Connor G, Grati M, Mittal J, Yan D, Eshraghi AA, Deo SK, Daunert S, Liu XZ. Neurotransmitters: The Critical Modulators Regulating Gut-Brain Axis. J Cell Physiol. 2017 Sep;232(9):2359-2372. doi: 10.1002/jcp.25518. Epub 2017 Apr 10. PMID: 27512962; PMCID: PMC5772764.

Chen Y, Xu J, Chen Y. Regulation of Neurotransmitters by the Gut Microbiota and Effects on Cognition in Neurological Disorders. Nutrients. 2021 Jun 19;13(6):2099. doi: 10.3390/nu13062099. PMID: 34205336; PMCID: PMC8234057.

Carabotti M, Scirocco A, Maselli MA, Severi C. The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems. Ann Gastroenterol. 2015 Apr-Jun;28(2):203-209. PMID: 25830558; PMCID: PMC4367209.

Mayer EA, Tillisch K, Gupta A. Gut/brain axis and the microbiota. J Clin Invest. 2015 Mar 2;125(3):926-38. doi: 10.1172/JCI76304. Epub 2015 Feb 17. PMID: 25689247; PMCID: PMC4362231.

Cryan JF, Dinan TG. Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour. Nat Rev Neurosci. 2012 Oct;13(10):701-12. doi: 10.1038/nrn3346. Epub 2012 Sep 12. PMID: 22968153.

Breit S, Kupferberg A, Rogler G, Hasler G. Vagus Nerve as Modulator of the Brain-Gut Axis in Psychiatric and Inflammatory Disorders. Front Psychiatry. 2018 Mar 13;9:44. doi: 10.3389/fpsyt.2018.00044. PMID: 29593576; PMCID: PMC5859128.

Clapp M, Aurora N, Herrera L, Bhatia M, Wilen E, Wakefield S. Gut microbiota's effect on mental health: The gut-brain axis. Clin Pract. 2017 Sep 15;7(4):987. doi: 10.4081/cp.2017.987. PMID: 29071061; PMCID: PMC5641835.

Mulder D, Aarts E, Arias Vasquez A, Bloemendaal M. A systematic review exploring the association between the human gut microbiota and brain connectivity in health and disease. Mol Psychiatry. 2023 Jul 21. doi: 10.1038/s41380-023-02146-4. Epub ahead of print. PMID: 37479779.

Older Post Newer Post